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Description

The information presented in this activity is not meant to serve as a guideline for patient management

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Participants randomized to retatrutide initiated treatment with 2 mg once weekly and increased the dose in a stepwise approach every four weeks until reaching the target dose of 4 mg (via steps at 2 mg and 4 mg), 9 mg (via steps at 2 mg, 4 mg, and 6 mg) or 12 mg (via steps at 2 mg, 4 mg, 6 mg, and 9 mg)

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Deep Dive: The GLP-1 Impact Background: Starting Tirzepatide (April 2024) In April 2024, I started Tirzepatide (Mounjaro/Zepbound) at 2.5mg, gradually escalating to 10mg over several months

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Therefore, even a disrupted and more permeable BBB can represent a serious challenge to brain-targeted drug delivery

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It means that a potential risk has been identified that was not previously known, and the magnitude of that risk has not yet been determined

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