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The more than 75% reduction in osteoarthritic knee pain scores was also superior to the 42% achieved with rival Novo Nordisks GLP-1 drug semaglutide
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In the approval trials, roughly five percent of participants reported hair loss, against around one percent on placebo
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Clinical trials required participants to follow structured lifestyle interventions with specific calorie restriction and physical activity goals, and real-world results may differ if these components are not implemented
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