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Weight-loss trajectories, demographic patterns, adverse-event profiles, and pre- to post-treatment disease-prevalence changes were compared across drugs
On the one hand, by regulating selenocysteine tRNA which in turn promotes GPX4 synthesis
Discussion In this database study, treatment with semaglutide (against sitagliptin, a placebo proxy) led to a reduced risk of MACE, and tirzepatide (against dulaglutide) demonstrated a similar risk reduction in patients at elevated cardiovascular risk with obesity and type 2 diabetes
doi: 10.1186/s12967-024-05579-9 37 ChengX
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