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A recent retrospective study involving a large sample size of 1,890,020 diabetic patients found that GLP-1RAs were associated with a significantly lower risk of hepatocellular carcinoma compared to insulin and other diabetic medications over a 5-year follow-up period (Wang et al., 2024a)
Approximately 100 cases were identified annually over six years, with the highest risk observed within the first year of medication use
Slower gastric emptying and more distal intestinal nutrient delivery tend to produce more sustained GLP-1 secretion
It should be viewed as a supplemental aid not a replacement
Wegovy Wegovy is another brand of semaglutide, but it is specifically used for weight management in adults who are overweight or obese
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