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Age-related anabolic resistance and reduced baseline muscle reserve may increase susceptibility to lean mass loss during medically induced weight reduction [40]

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Adems, el tratamiento de lixisenatida ms insulina se acompaa de una reduccin de peso significativa en comparacin con el de insulina basal(16)

Enzymatic cleavage of albumin results in less efficient FcRn-mediated rescue from lysosomal degradation and, consequently, a dramatically shorter plasma half-life of 3.5 days in humans 60