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This interaction triggers TRIM25-mediated K48-linked ubiquitination of GPX4 and induces ferroptosis [62]
Abstract The spectrophotometric/microplate reader assay method for glutathione (GSH) involves oxidation of GSH by the sulfhydryl reagent 5,5-dithio-bis(2-nitrobenzoic acid) (DTNB) to form the yellow derivative 5-thio-2-nitrobenzoic acid (TNB), measurable at 412 nm
Ten-Day Decitabine with Venetoclax (DEC10-VEN) in Acute Myeloid Leukemia and Myelodysplastic Syndrome: Updated Results of a Phase II Trial
Cells then recycle it back using an enzyme (glutathione reductase), creating a powerful protection cycle
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