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The conjugation of glutathione on the previously hydrophobic-toxic substrate results in a soluble compound, which is more readily exocytosed by the cell
Options your provider may consider include extending the time between dose increases to give your gut more time to adapt, temporarily reducing the dose until constipation management strategies take effect, or switching between GLP-1 medications if one produces intolerable side effects
Tapeworms eat vitamin B12
Frequency depends on the protocol and your individual health picture
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