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Phentermine/topiramate (Qsymia) is taken once daily
The dual composite endpoint of HbA1c below 7% plus 10% or more weight loss was achieved by 48% of mazdutide patients versus 21% on semaglutide
Ipamorelin is reported in smaller studies to cause fewer cortisol and prolactin side effects compared to older GHRP secretagogues like GHRP-6
Ondansetron (48 mg as needed) is a serotonin 5-HT3 receptor antagonist that can be effective for GLP-1 agonist-related symptoms, though it may cause constipation, headache, and can prolong the QT interval in susceptible individuals
Mishra B, Barik A, Kunwar A et al (2008) Correlating the GPx activity of selenocystine derivatives with one-electron redox reactions
