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pmc.ncbi.nlm.nih.gov/articles/PMC10338602 Zeng K, et al

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Adverse Reactions/Side Effects The following important adverse reactions observed with the use of Depo-Provera CI are discussed in greater detail in the Warnings and Precautions section (5): Loss of Bone Mineral Density [see Warnings and Precautions (5.1)] Thromboembolic disease [see Warnings and Precautions (5.2)] Breast Cancer [see Warnings and Precautions (5.3)] Anaphylaxis and Anaphylactoid Reactions [see Warnings and Precautions (5.6)] Bleeding Irregularities [see Warnings and Precautions (5.11)] Weight Gain [see Warnings and Precautions (5.12)] 6.1 Clinical Trials Experience Clinical trials are conducted under widely varying conditions, therefore, adverse reaction rates observed in the clinical studies of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice

Additionally, individuals should incorporate diverse strategies to achieve well-being, recognizing that supplements may serve only as part of a broader approach

Only pharmaceutical-grade diluents, used in accordance with the relevant SmPC and under professional supervision, should ever be considered