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Commenting on PRACs recommendations, a spokesperson for Novo Nordisk said: Based on the totality of evidence, we concluded that the data did not suggest a reasonable possibility of a causal relationship between semaglutide and NAION and that the benefit-risk profile of semaglutide remains favourable

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This escalation is intentional

The combined use of these medications was first reported in 2014 [61], and the number of studies has grown exponentially since then

The best choice depends on how the peptide will be used