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Concerns about the potential association between certain diabetes medications and cardiovascular disease meant that in 2010 the FDA approved liraglutide on condition that Novo Nordisk conduct a post-marketing study to evaluate the drug's effect on the incidence of major cardiovascular events (Nielsen, DeChiaro, Goldman)

As we age, preserving muscle becomes increasingly important for maintaining a healthy metabolic rate

In addition, another study demonstrated that the inhibition of GLP-1R in brain aggravates glucose homeostasis and insulin sensitivity (Knauf et al., 2008)

Natl Health Stat Report 2021(158)

It is also a promising drug for treating AKI (Figure 4A) (Wang et al., 2022)