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Additionally, PRMT5 can symmetrically dimethylate the arginine residue at position 152 of GPX4, enhancing GPX4 stability and inhibiting ferroptosis[148][158]
[14] [15] In those studies, the lowest dose (600 mg) tended to be as well-tolerated as placebo, with no significant difference in adverse events compared to placebo
Ann Neurosci 26:25
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