Published data from TRIUMPH-1 and TRIUMPH-4 show that discontinuation rates rise with dose
Marino-Merlo et al., 2016)
Therefore, slowed gastric emptying from the stomach to the upper intestine (duodenum) observed after GLP-1 agonist administration could lead to increased levels of acetaldehyde and an altered or blunted rise in blood alcohol content (BAC)
So even as were doing research, were not entirely sure why it works so well in the brain, but appetite is controlled. Fehl wants to remind patients that weight loss is achieved by a combination of efforts rather than simply relying on Ozempic and its counterparts, no matter how effective they may be
Topaloglu R, Gultekingil A, Gulhan B, Ozaltin F, Demir H, Ciftci T, Demir N, Temucin CM, Yuce A, Akhan O (2020) Cystinosis beyond kidneys: gastrointestinal system and muscle involvement