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Furthermore, in ECL1 of GCGR there are two glycine residues (G207 ECL1 , G219 ECL1 ) that disconnect the helical structure in the active state, whereas the G219 ECL1 is not conserved in GLP-1R and the helical conformation is relatively intact in this region of GLP-1R

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van Erven L, Schalij MJ (2010) Amiodarone: an effective antiarrhythmic drug with unusual side effects

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