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Injection sites should be rotated systematically across the abdomen, thighs, and upper arms to prevent lipohypertrophy and ensure consistent absorption

Constipation : Some individuals may experience difficulty in passing stools

Patients should also tell surgical and anesthesia teams about GLP-1 or tirzepatide treatment before procedures involving general anesthesia or deep sedation because current labeling includes warnings related to delayed gastric emptying and pulmonary aspiration

[PMID: 18230920] PubMed record related to this compound for laboratory literature review