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Am J Kidney Dis (1998) 32(6):91733
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As a key methyltransferase of m6A, METTL3 can inhibit the activation of pTHP-1 macrophages by preventing the generation of IL-6 and TNF-, and attenuate inflammatory response induced by LPS via the NF-B signaling pathway (178)
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In addition, the taurine/cysteine and cysteine/(serine + methionine) ratios, which reflect oxidative cysteine catabolism and cysteine synthesis, respectively, increased and decreased, respectively, in both cord blood vessels (Fig
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