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The molecule consists of a corrin ring coordinated to a central cobalt ion with a cyano ligand at the upper axial position and a 5,6-dimethylbenzimidazole nucleotide at the lower axial position

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Materials and methods Animals and experimental design Nine-week-old male Fischer 344 rats (Charles River Laboratory, Japan), weighing from 180-200 g, were maintained at 23C, given standard laboratory chow and water ad libitum, and kept under a 12 h light (7:00-19:00)/12 h dark schedule