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The liver produces ceruloplasmin and excretes excess copper through bile
However, targeting ferritin in epithelial tumors should not be completely ruled out as removal of the iron buffering system within the cell makes them more susceptible to iron-dependent (ferroptotic) cell death [121, 122]
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Reach for this in Fitzpatrick IVVI, especially if post-inflammatory hyperpigmentation shadows every lesion
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