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Tolerance In other instances, the medication may have worked at least initially but it doesnt seem to be working as well anymore

Using the same spot repeatedly can lead to lipohypertrophy (fatty lumps under the skin), which can affect how well the medication is absorbed

In some cases, the fat might not dissolve evenly, leading to lumps or uneven results, which can require additional treatments to correct

As a general principle applicable to reconstituted peptide solutions, such preparations are more vulnerable to degradation than their lyophilised (freeze-dried) counterparts

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