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By binding and sequestering G-actin with high affinity, the active region is described as regulating actin polymerisation, which in turn supports cell migration , proliferation and differentiation

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Key areas of investigation include modulation of the nitric oxide (NO) system through interaction with NOS isoforms, upregulation of growth factor receptors (including VEGFR2 and EGF receptor systems), and engagement of the FAK-paxillin signaling cascade associated with cell migration and adhesion