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Clinical trial data shows nausea affects between 15.4% to 43.9% of users depending on dose and formulation, with higher doses producing increased incidence

In a randomized clinical trial , adults with obesity or overweight (but without diabetes) who took Saxenda experienced an average weight loss of 6.4% in 68 weeks (about a year and a half)

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This complex is then shuttled across the inner mitochondrial membrane by a specialized enzyme called carnitine palmitoyltransferase I (CPT1)