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(2009) Medicinal Chemistry Approaches to the Inhibition of Dipeptidyl Peptidase-4 for the Treatment of Type 2 Diabetes

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All patients complete a medical evaluation and informed consent before beginning treatment

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Signal sensitivity pulsed dosing is the conservative way to avoid blunting the response over time

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10.7326/0003-4819-113-12-909 81 WildingJ

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Activation of these receptors may modulate dopamine signaling, potentially reducing alcohol's rewarding properties, though the exact mechanisms in humans remain under investigation

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