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Under non-apoptotic conditions, Bax is inactive and present in the cytosol as a monomer

doi: 10.1016/j.jprot.2020.103684 47

Second, time-varying confounding due to informative censoring could be present in as-treated analyses, while an intention-to-treat analysis is not susceptible to treatment-related informative censoring

The tradeoff is that you're getting astaxanthin alone

The committee is considering an atypical regulatory pathway, allowing these substances to be compounded rather than going through the full, rigorous FDA approval process