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Why do I need B12 supplements if I'm eating protein on tirzepatide

J Pharmacol Exp Ther 187:211217 Mandl J, Bnhegyi G, Kalapos MP, Garz T (1995) Increased oxidation and decreased conjugation of drugs in the liver caused by starvation

This aligns with drug reaching its highest concentration in bloodstream

Endod (2)102:204216

It has been shown to upregulate pathways tied to collagen and glycosaminoglycan synthesis, modulate metalloproteinase (MMP) and tissue inhibitor of metalloproteinases (TIMP) balance, and support antioxidant effects, thereby contributing to matrix organization and structural stability in research settings