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doi:10.1016/j.ghir.2009.03.001 (source) Henninge J, Pepaj M, Hullstein I, Hemmersbach P
Details of the antibodies and assay given in supporting information file
GC18705 ML-210 DPI10 ML-210 is a prodrug that selectively inhibits GPX4 covalently with an EC 50 of 30nM
This higher activity results from the insensitivity of ETC to FCCP treatment and is consistent with the limited reserve capacity of Gclc -deficient FoB (Fig
The principle of this reaction is based on the reaction between the thiol group (-SH) of glutathione and the DTNB reagent, which results in the formation of a colored product
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