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However, it is an important and increasingly discussed area of research

Individual plots from different studies are shown in Figure 3D

The goal of research is not simply to determine which molecule is better, but to understand how each behaves under different experimental conditions

CAR-T therapies like Novartiss Kymriah (tisagenlecleucel) and Gilead/Kites Yescarta (axicabtagene ciloleucel), lentiviral gene therapies like bluebird bios betibeglogene/Zynteglo, adeno-associated virus (AAV)-based programs like Sareptas Elevidys (delandistrogene moxeparvovec) and CSL Behrings Hemgenix (etranacogene dezaparvovec), and gene editing programs using CRISPR/Cas9 or base editing technologies, all involve manufacturing processes of extraordinary complexity that cannot be adequately protected by conventional composition-of-matter patents alone

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