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The authors point out that doxycycline-associated skin hyperpigmentation seems to be uncommon and they summarize 18 patients in the literature with this side effect

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In this trial, once-weekly cagrilintidesemaglutide for 68 weeks in adults with overweight or obesity was highly effective and led to substantial and clinically meaningful weight loss

Additionally, they argue that the real focus should not be on those individuals whose level of intoxication rarely leads to traffic accidents or fatalities, but rather on those repeat offenders and heavy drinkers responsible for most of the alcohol related traffic accidents and fatalities

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