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published a propensity score-matched study of 1123 Mediterranean G6PD-d subjects, the largest sample size of G6PD-d subjects to date, which showed a 71% higher risk of ASCVD after controlling for available ASCVD-related covariates 19
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DNA Damage and Mutations: The increase in etheno dG and dA DNA adducts, caused by lipid peroxidation in liver tissues from hemochromatosis patients, and the p53 mutational load in liver tissue from individuals with hemochromatosis are both consistent with the hypothesis of generation of oxyradicals as an underlying mechanism of cancer in heavy metal overload diseases
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