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The lack of Vitamin B12 in the diets of vegetarians has challenged researchers to develop veganic and vitamin-enriched dietary resources and supplements

Vitamin B12 deficiency can cause a variety of symptoms, and they can vary depending on the severity and duration of the deficiency

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Research looks into its use for peripheral neuropathy, multiple sclerosis-related pain, and other nerve damage

This timeline matches B12 pharmacokinetics: intramuscular methylcobalamin reaches peak serum concentration at 8-12 hours, but tissue saturation (particularly in the liver and nervous system) occurs over 48-72 hours as the vitamin is transported into cells and converted to active coenzyme forms (Andrs et al., 2018)