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The anorectic and thermogenic effects of OXM were also demonstrated in overweight and obese humans, where chronic administration with native OXM resulted in modest weight loss without any detectable adverse effects [82,83,84]
Obesity (Silver Spring) 14 (2), 194198 (2006)
Treatment was associated with fibrosis improvement by at least one stage with no worsening in non-alcoholic fatty liver disease (NAFLD) activity score in 25% of resmetirom recipients versus just under 15% in the placebo group
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