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Since the body cannot produce B12 on its own, it must be obtained through diet or supplements

Increased MMP-2 and MMP-9 expression and activity can affect BBB permeability by proteolysis of extracellular matrix and structural proteins in brain endothelial cells, increasing the BBB breakdown (Figure 2) (Yang et al., 2007

Other groups that are at a greater threat of having a vitamin B12 deficiency consist of cigarette smokers (given that nicotine could obstruct absorption), alcoholics, those with anemia, and any individual with a gastrointestinal condition like Celiac or Crohns illness

The effect of folate fortification on folic acid-based homocysteine-lowering intervention and stroke risk: a meta-analysis

Going slower beats fighting through