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Despite these limitations, the majority of existing studies suggest that therapies aimed at reducing uric acid levels may potentially attenuate the progression of CKD
It also generates foam
Furthermore, it was found that the general control of amino acid synthesis 5-like 1 (GCN5L1) negatively regulates both mitochondrial biogenesis and degradation pathways through acting on both PGC1a and TFEB in mouse embryonic fibroblasts (Scott et al., 2014)
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