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Quick Answer: GLP-1 medications show clinically meaningful average weight loss in large-scale peer-reviewed trials - approximately 14.9% for semaglutide (STEP 1) and up to 20.9% for tirzepatide (SURMOUNT-1) under trial conditions
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Please note: While some medications available through Gala GLP-1 are FDA-approved for weight management, compounded medications are not reviewed or approved by the FDA
10.1146/annurev.me.40.020189.002211
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