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Although the central roles of mtROS, mtDNA leakage, and the NLRP3/cGAS-STING pathways in driving chronic inflammation in DW have been established, the specific regulatory networks of these events across different stages of wound healing and various cell types (such as macrophages, fibroblasts, and keratinocytes) remain unclear

3 Rubino DM, Greenway FL, Khalid U, ONeil PM, Rosenstock J, Srrig R, Wadden TA, Wizert A, Garvey WT

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