CagriSemas REIMAGINE 13 program, presented at ADA 2026 and published simultaneously in The Lancet and The Lancet Diabetes & Endocrinology, showed superior HbA1c reduction and weight loss compared with semaglutide alone across multiple type 2 diabetes populations, including basal-insulin-treated patients in whom add-on CagriSema lowered HbA1c from 8.8% to 6.5% with up to 12% weight loss and no severe hypoglycemia
These are seen as a consequence of rapid weight loss rather than a direct side effect of GLP-1 drugs
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Protein supplementation augments the adaptive response of skeletal muscle to resistance-type exercise training: a meta-analysis