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Patients should check their benefits to confirm coverage and explore prior authorization requirements if needed. Dr

Zhao et al., 2021a)

Filter-sterilize through a 0.22 m low-protein-binding filter before introduction into sterile cell culture, and prepare working dilutions immediately before use

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Identification of the exact mechanism for the lethal effect of silencing the enzyme requires further experiments, as do the effects of inhibitors, which are not necessarily solely due to loss of enzyme activity, because the inhibited enzyme may also have a gain of function leading to cell death [72]