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Per results of a phase 1 study, a long-acting GIPRA used in combination with a rapidly escalated, selective GLP-1RA demonstrated mild weight loss with reduced gastrointestinal adverse events in participants with or without T2D [17]
GLP-1 medications have been shown in clinical trials to help people lose significant amounts of weight, results that used to be associated mainly with bariatric surgery
L.SanteramoA.RocaE.CoccoT.et al (2022)
There may be a bit of tingling, but its very manageable
Studies suggest it may raise GH levels by 2001000% and increase mean plasma IGF-1 concentrations by 1.53 fold, with effects persisting for 68 days under experimental conditions
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