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Labonia WD, Morelli OH Jr, Gimenez MI, Freuler PV, Morelli OH

Pro-inflammatory M1 macrophages show enhanced glycolysis and PPP flux which provides more energy and NADPH to trigger inflammatory responses, secrete pro-inflammatory cytokines and recruit more immune cells

That sustained rise can cause swelling and fluid retention, and has been linked to hormonal imbalances, disruption to ovarian function and a higher risk of miscarriage

DRcaps size 0 capsules (Capsugel, Lonza, Slough, UK) were loaded into the filling device, and pomegranate extract or placebo contents were dispensed, spread using a powder spreader, and sealed

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