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645 Protoplasmic (but not fibrous) astrocytes protect against -synuclein toxicity by removing this latter through endocytosis, 646,647 and hence astrocytic atrophy reduces neuroprotection
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In contrast, a recently conducted randomized multicenter phase III trial found that extended LND did not offer significant advantages over standard LND with respect to patient overall, cancer-specific, or recurrence-free survival
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