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And muscle mass is the key piece to consider when it comes to this
It is plausible that retatrutide could offer similar benefits in this group given its potent metabolic effects, but this has not been directly studied
Trial participants were randomized to tirzepatide or placebo, and primary outcomes were time to cardiovascular death or worsening HF and change in KCCQ-Clinical Summary Score (CSS) at 52 weeks
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However, anecdotal evidence and small-scale studies suggest that combining semaglutide with other agents can be beneficial for some patients, particularly those with significant obesity-related comorbidities
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