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The Stable Gastric Pentadecapeptide BPC 157 Pleiotropic Beneficial Activity and Its Possible Relations with Neurotransmitter Activity

174 Previous studies have reported the comprehensive effects of GLP-1RA on the CNS, which go beyond the levels of blood glucose modulation, but are associated with numerous metabolic aspects such as food intake and preference, 127,175 water intake, 176 energy expenditure, 177 body weight reduction, 178 pancreatic function, 132,179,180 hypertension, 181 stress, 182 addiction behaviors, 183,184 as well as neurodegenerative disorders, such as Alzheimer and Parkinson diseases

However, tirzepatide was removed from the FDA drug shortage list, triggering restrictions on compounded versions

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Kailera plans to start global Phase 3 trials as soon as first half 2027 ( [49] )