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Key identifiers: IUPAC name: (2S)-2-amino-4-[[(1R)-1-[(carboxymethyl)carbamoyl]-2-sulfanylethyl]carbamoyl]butanoic acid Also known as: GSH, L-glutathione, gamma-L-glutamyl-L-cysteinylglycine CAS Number: 70-18-8 Endogenous production: Yes
At present, NAC is a convenient, safe, oral drug that can increase the glutathione content in the blood while also reducing homocysteine levels, and an increase in the latter can lead to neuronal degeneration and severe neuropathy [61]
For example, charcoal adsorbs toxins as opposed to tightly binding toxins
Its safety profile has been well-established in clinical trials, with no significant adverse effects reported
Neurochem Res 34:19621968 Pong WW, Stouracova R, Frank N, Kraus JP, Eldred WD (2007) Comparative localization of cystathionine beta-synthase and cystathionine gamma-lyase in retina: differences between amphibians and mammals
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