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However, the definitive Exenatide-PD3 phase 3 trial , published in The Lancet in February 2025, found no disease-modifying benefit exenatide did not slow Parkinsons progression over 96 weeks compared to placebo in 194 patients ( [25] )
Continuing lifestyle changes and, if appropriate, transitioning to metformin or another agent can blunt rebound
Altogether, women find that using GLP-1s alongside a balanced diet and regular exercise makes it easier to maintain a healthy weight during perimenopause, reducing the physical and emotional strain that weight fluctuations can bring
However, a negative point is that there are no third-party quality assurance and testing reports
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