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in addition, the regulatory mechanism of d-carnitine on nutritional metabolism in fish was not yet known now ( Reference Santulli and DAmelio 23 , Reference Santulli and DAmello 28 )

Significant evidence from large, randomised trials has shown that SGLT2Is have a positive impact on heart failure with reduced ejection fraction (HFrEF) as well as on HFpEF

It may promote abnormal angiogenesis (new blood-vessel growth), raising theoretical concerns in patients with cancer history

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