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The FDA explains that compounded drugs are not FDA-approved , meaning the agency does not verify their safety, effectiveness, or quality before marketing (see Compounding and the FDA: Questions and Answers )

Detoxification: Unlike cyanocobalamin, which contains a cyanide molecule that must be detoxified and excreted by the body, Methylcobalamin does not pose this additional burden on the detoxification systems

Its worth noting that liquid vitamin B12 supplements often contain other ingredients, like fruit and vegetable extracts, glycerin, sweeteners, and more

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