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Picture this: testing a new swimming pool by only allowing people who cant swim to stand on the deck, declaring it safe based on the zero drownings, and then opening it to the public with a sign that says PROBABLY FINE. We then gave it to millions of people, many of whom have brain chemistry that is already struggling, and we are now acting confused about the results
The active ingredient, mechanism of action, and dosing schedule are identical
Gradually increase the dose to reduce the chance of gastrointestinal side effects and reach the maintenance dose
Brain metabolism dictates the polarity of astrocyte control over arterioles
The FDA has been explicit about this distinction
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