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The activated NF- B rapidly translocated from the cytoplasm into the nucleus, binds to specific DNA sequences, induces the expression of several proinflammatory cytokine genes, and promotes the massive release of proinflammatory cytokines such as TNF- , IL-1, and IL-6 (Xu et al., 2022)

Antioxidant therapy represents a promising intervention to mitigate the harmful effects of ROS on reproductive health in additions to its easy accessibility, safety, and low cost

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