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Hyperpigmentation Reduction Glutathione inhibits melanin production, meaning it can lighten up dark patches, age spots, and post-inflammatory hyperpigmentation

Uroevi M, Nikoli L, Gaji I, Nikoli V, Dini A, Miljkovi V

[6] Regulation [edit] When GLUD1 is highly saturated with the active site ligands (substrates), an inhibitory abortive complex forms in the active site: NAD(P)H.Glu in the oxidative deamination reaction at high pH, and NAD(P) + .2-oxoglutarate in the reductive amination reaction at low pH

doi: 10.1016/S2213-2600(17)30306-5 229 SharmaRKumarSDhasmanaDKalraJ

3 Hence, through the histopathological examination of melanocyte activity, location of melanin pigment deposition, and response after therapy, we can determine the effects of glutathione on skin color