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By defining global and gene-specific DNA 5hmC modifications, we demonstrated that DMF induces 5hmC modifications to influence loci-specific chromatin structure through L2HGDH to reduce the levels of L2HG
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Blood-brain barrier dysfunction, seizures and epilepsy
DAC (Drug Affinity Complex) binds to albumin in the bloodstream, which dramatically extends the peptide's half-life
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