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Milk thistle (Silybum marianum) is a Mediterranean plant whose seeds contain silymarin, a group of antioxidant plant compounds

Clinical trial protocols from the Phase 2 NEJM study used a gradual escalation approach, starting at low doses and increasing every four weeks

Not intended to diagnose, treat, cure, mitigate, or prevent disease

The layers of an onion concentrate these beneficial compounds, making them readily available when you include onions in your regular diet

Research evidence The pivotal efficacy evidence comes from two identically designed Phase 3 randomized placebo-controlled trials run by Theratechnologies and reported by Julian Falutz and colleagues in the New England Journal of Medicine in 2007 (Falutz et al., NEJM 357:2359-2370)